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BETA2 CONNEXIN
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DeCS
Descriptor
English
:
Connexin 26
Descriptor
Spanish
:
Conexina 26
Descriptor
Portuguese
:
Conexina 26
Synonyms
English
:
26, Connexin
Connexin Cx26
Connexin beta 2
Connexin beta-2
Connexin, beta2
Cx26, Connexin
Gap Junction beta 2 protein
Gap Junction beta-2 protein
beta-2, Connexin
beta2 Connexin
Tree Number:
D12.776.543.585.250.100
Definition
English
:
A gap junction protein encoded by the Gap Junction Beta 2 or GJB2 gene. In the
cochlea
and
epidermis
, its hexamers form channels between cells that open to allow cell-to-cell
diffusion
of small molecules as well as
recycling
of
potassium
.
Mutations
in
Connexin 26
are associated with congenital SENSORINEURAL
HEARING LOSS.
History Note
English
:
2017 (1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56638
Unique Identifier:
D000072259
Occurrence in VHL
:
Similar:
DeCS